Theoretical and Computational Neuroscience<\/p>\n
Author:<\/strong> Jim\u00e9nez Armas Lijandy | Email:<\/strong> lijandy92@gmail.com<\/p>\n Lijandy Jim\u00e9nez Armas 1\u00b0<\/sup>, Constantino M\u00e9ndez B\u00e9rtolo 2\u00b0<\/sup>, Florencia Sanmart\u00edno 3\u00b0<\/sup>, Fernando L\u00f3pez Sosa 2\u00b0<\/sup>, Ra\u00fal Rashid L\u00f3pez 4\u00b0<\/sup>, Ra\u00fal Espinosa Rosso 4\u00b0<\/sup>, Javier Gonzalez Rosa 3\u00b0<\/sup>, Diego M Mateos 1\u00b0<\/sup><\/p>\n 1\u00b0 Instituto de Matem\u00e1tica Aplicada del Litoral (IMAL-CONICET-UNL), 3000, Santa Fe, Argentina Parkinson’s disease stands out as a prominent neurodegenerative disorder with profound impacts on both movement and muscular control, affecting a global community of over 6 million individuals. Among the array of available treatments, Deep Brain Stimulation (DBS), characterized by the implantation of cerebral electrodes, has emerged as a highly effective intervention. By delivering electrical pulses, DBS alleviates motor symptoms such as tremors and rigidity, thereby enhancing patients’ overall quality of life. However, beneath its impressive efficacy, a pivotal question lingers: What precisely unfolds within the cerebral dynamics of a person with Parkinson’s, and how does DBS modulate these dynamics?<\/p>\n To unravel this intricate inquiry, our investigation delved into a meticulous analysis of high-density EEG records sourced from Parkinson’s patients experiencing both active and inactive DBS, juxtaposed against a control group. Employing classical metrics like power spectrum and drawing from information theory, encompassing entropy and complexity, we aimed to uncover nuanced shifts in neural patterns and responses induced by DBS.<\/p>\n Our results reveal significant differences in the power spectrum and information quantifiers between control subjects and those with Parkinson’s when DBS is turned off. However, these differences noticeably diminish when DBS is turned on. This suggests that brain dynamics are indeed impacted by Parkinson’s disease, yet the implementation of DBS tends<\/p>\n","protected":false},"excerpt":{"rendered":" Author: Lijandy Jim\u00e9nez Armas | email: lijandy92@gmail.com | Theoretical and Computational Neuroscience<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[28],"class_list":["post-1364","post","type-post","status-publish","format-standard","hentry","category-session-1","tag-theoretical-and-computational-neuroscience"],"_links":{"self":[{"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/posts\/1364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/comments?post=1364"}],"version-history":[{"count":3,"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/posts\/1364\/revisions"}],"predecessor-version":[{"id":1858,"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/posts\/1364\/revisions\/1858"}],"wp:attachment":[{"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/media?parent=1364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/categories?post=1364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csan2023.saneurociencias.org.ar\/index.php\/wp-json\/wp\/v2\/tags?post=1364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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\n2\u00b0 Department of Psychology, University of Cadiz, 11003 Cadiz, Spain
\n3\u00b0 Institute of Research and Biomedical Innovation of Cadiz (INiBICA), 11009 Cadiz, Spain
\n4\u00b0 Department of Neurology, Puerta del Mar Universitary Hospital, 11009 Cadiz, Spain<\/p>\n